Hilton reports in the SBS2k listserve….
If you are running NOD32 with XMON enabled (the Exchange Server plugin)
and have the 2022 update downloaded and running, then Exchange
Information Store will fail. Disable XMON, restart Exchange, and wait
for an updated database. This issue has been reported to ESET.
The fix is to ensure that you exclude additional log files such as the Exchsrvr\server_name.log directory.
….while you are at it.. review this one too….