A workaround has been published for this false positive affecting SAP connectivity software.
McAfee Virus Scan DAT 6329 False Positive
QUOTE: McAfee Labs have issued an alert that McAfee VirusScan DAT file 6329 is returning a false positive for spsgui.exe. This is impacting SAP telephone connectivity functionality
McAfee have a work around for the issue documented in KB71739