Do you want your emails to family and friends to have a signature that is personal and fun but want to your business emails to have professional signature.
One way to accomplish this is to have multiple email accounts configured in Outlook for different puproses. I have setup one as my personal (family & friends) account and one is for business and the other generic.
Once I had this setup I then went into Outlook, Tools – Options – Mail Format – Signatures to write signatures for each of these accounts and specify to have it on all new and/or replies and forwards.
Just remember you will need to specify the account you are sending from on New Messages. But still a great feature to setup.