Microsoft release a new KB for ISA Server w/ Windows Server SP2.
“You are using a Microsoft Windows Server 2003 Service Pack 2 (SP2)-based multiprocessor computer that is running Microsoft Internet Security and Acceleration (ISA) Server 2006 or Microsoft ISA Server 2004. With this configuration, you experience the following symptoms:
• CPU use for a particular processor reaches 100 percent.
• The total throughput of ISA Server is greatly reduced or completely blocked.
• Latency increases significantly even though other processors are used at much reduced levels.
Note This problem occurs only on multiprocessor computers that use 32-bit processors.
This problem occurs because of the “lazy Interrupt Request Level” (IRQL) handler that is included in Windows Server 2003 SP2.
To resolve this problem, use the Interrupt-Affinity tool to assign the interrupts of different network adapters to different processors. …” See link below.
MVP Windows Server System – ISA Server
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