I would like to point your attention to cool OpenSource project this time, OSSIM. At work we make use of this tool to mosaic different aerial images for example. But it can do a lot other image manipulating related tasks as well, like color matches between different images or reprojecting images to a different projection. So have a look at this awesome tool.
While reading the manual of OSSIM, I noticed that it should also be able to do image tiling. This could be a useful feature when trying to make the tiles for a high resolution ground layout. But I haven’t been able to get that feature working completely, I’ll make a new post about this once I got it fully working.