Thanks to Chris Puckett and his team for working on this to get a resolution. We have seen this primarily with Trend Micro (our primary anti-virus product) but it is happening with any product using TDI, so if you are getting similar behavior from your server(s), get this hotfix! See the SBS blog post.
Had an email today on this asking if it is okay for EBS. Yes, this fix will work for both SBS 2008 and EBS 2008.
Steve